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It would be interesting to know more about the hypoglycemia link. I contracted type one diabetes as an adult, somehow, and was hesitant to try anything for the
by code_duck 5y ago
It would be interesting to know more about the hypoglycemia link. I contracted type one diabetes as an adult, somehow, and was hesitant to try anything for the first time after that including alcohol or cannabis. I wear a continuous glucose monitor and as far as I can tell, cannabis has no effect on my blood glucose.
- mullingitover 5y agoThere's this study published in Diabetes Care[1], "Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study". > RESULTS Compared with placebo, THCV significantly decreased fasting plasma glucose (estimated treatment difference [ETD] = −1.2 mmol/L; P < 0.05) and improved pancreatic β-cell function (HOMA2 β-cell function [ETD = −44.51 points; P < 0.01]), adiponectin (ETD = −5.9 × 106 pg/mL; P < 0.01), and apolipoprotein A (ETD = −6.02 μmol/L; P < 0.05), although plasma HDL was unaffected. Compared with baseline (but not placebo), CBD decreased resistin (−898 pg/ml; P < 0.05) and increased glucose-dependent insulinotropic peptide (21.9 pg/ml; P < 0.05). None of the combination treatments had a significant impact on end points. CBD and THCV were well tolerated. [1] https://care.diabetesjournals.org/content/39/10/1777.long https://care.diabetesjournals.org/content/39/10/1777.long
- code_duck 5y agoIn the case of type 2 diabetes patients, reducing fasting plasma glucose is exactly what you would want to do since chronic hyperglycemia is the major issue in that condition. It’s not clear if it would work the same for type 1 or non-diabetic people.