4 ms·
To be clear, there is science that is compatible with THC increasing the risk of psychosis (and perhaps that CBD is protective). I would agree that some are se
by thaw13579 5y ago
To be clear, there is science that is compatible with THC increasing the risk of psychosis (and perhaps that CBD is protective). I would agree that some are self medicating, but the data also shows that dosage, THC/CBD mixture, and age of use each elevate psychosis risk over random controls [1][2].
It would be great to do double blinded experiments to test this more definitely, but we don't due to unethical reasons. I think the differential legalization will provide useful data along those lines, though it will take some years.
I also think it's important to distinguish between THC "exacerbating" an existing mental illness and triggering psychosis in otherwise healthy people who have a predisposition, due to genes and early life experience. We still don't have a clear idea exactly how to say who's predisposed. Plenty of reasons to take caution, in my opinion.
[1] https://www.nap.edu/catalog/24625/the-health-effects-of-cannabis-and-cannabinoids-the-current-state https://www.nap.edu/catalog/24625/the-health-effects-of-cann...
[2] https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(19)30048-3/fulltext https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0...
- jklinger410 5y agoI'm not trying to form a distinction between exacerbating and triggering psychosis in people who have a predisposition. But I think it's unfair to call them "otherwise healthy" as their psychosis, BPD, bi-polar, etc can manifest at any point in their life. It's fair to say that it triggers the early onset of a "dormant" mental disorder. My point being to say that it "causes" anything other than that trigger is currently unsupported.