Yes, this is what I do. You just set a DNS record on a subdomain, e.g. matrix.mydomain.com, and use that as your home server. Your username can still be @me:myd

Yes, this is what I do. You just set a DNS record on a subdomain, e.g. matrix.mydomain.com, and use that as your home server. Your username can still be @me:mydomain.com with this setup.