Proxmox is basically Debian plus some VM hypervisor stuff. So your question really is would someone recommend it if they're running Debian, as all that desktop

Proxmox is basically Debian plus some VM hypervisor stuff. So your question really is would someone recommend it if they're running Debian, as all that desktop environment stuff would be outside of what proxmox manages. Debian is super reliable - potentially the most reliable linux distro - but this wouldn't be a turnkey solution or anything (for example PopOS, based on Debian via Ubuntu, focuses more on the out-of-the-box experience). I don't know if Debian can handle your particular needs, but my assumption is that if any distro can Debian can - it just might take some time. Personally I love proxmox as a main operating system, as I can get everything from broader Debian/Ubuntu/PopOS environments and learn a lot about Linux too. But, it has taken a lot of my time, so I'd only recommend it if you wanted to invest the time.