"In 1998, Professors Raphael Mechoulam and Shimon Ben-Shabat posited that the endocannabinoid system demonstrated an “entourage effect” in which a variety of “i

"In 1998, Professors Raphael Mechoulam and Shimon Ben-Shabat posited that the endocannabinoid system demonstrated an “entourage effect” in which a variety of “inactive” metabolites and closely related molecules markedly increased the activity of the primary endogenous cannabinoids, anandamide and 2-arachidonoylglycerol" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334252/#:~:text=In%201998%2C%20Professors%20Raphael%20Mechoulam,cannabinoids%2C%20anandamide%20and%202%2Darachidonoylglycerol https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334252/#:~:tex...