The number of people needed for a trial depends on the size of the effect. I think we have a warped idea of that, because of the practice of looking for a bare

The number of people needed for a trial depends on the size of the effect. I think we have a warped idea of that, because of the practice of looking for a barely "statistically significant" effect from a substance that isn't really understood. If you have something that just eradicates a disease immediately, because you really understand what you are doing, you don't need very many tests to confirm it works.