Quanta Magazine [1] has an interesting article about how vaccines can help pathogens evolve to be more virulent, a particularly interesting part: > After the p

Quanta Magazine [1] has an interesting article about how vaccines can help pathogens evolve to be more virulent, a particularly interesting part: > After the parasites circulated through 21 rounds of vaccinated mice, Barclay and Read studied them and compared them to malaria parasites that had circulated through 21 rounds of unvaccinated mice. The strains from the vaccinated mice, they found, had grown far more virulent, in that they replicated faster and killed more red blood cells. At the end of 21 rounds of infection, these more quickly growing, deadly parasites were the only ones left. As a sibling mentioned, it doesn't appear to be as bad as bacterial resistance, or at least different in a nuanced way. From what I've read there is a difference between vaccinating _before_ a pandemic and vaccinating _during_ a pandemic. With the safer preference being to vaccinate before a pandemic to avoid immunological escape. [1] https://www.quantamagazine.org/how-vaccines-can-drive-pathogens-to-evolve-20180510/ https://www.quantamagazine.org/how-vaccines-can-drive-pathog...