Does anyone have any experience with high reliability applications with these types of boards? I'm thinking closer to consumer or industrial products, but not

Does anyone have any experience with high reliability applications with these types of boards? I'm thinking closer to consumer or industrial products, but not person-rated vehicles or medical applications. It seems that these are quite capable boards and designed for accessible and more rapid development, which could be great for getting some projects/products off the ground with lower development risk (as long as we aren't just substituting in hardware risk).