4 ms·
What's the alternative? Allow snakeoil? Now insurance has to cover it, incentivizing the creation of more ineffective drugs? Trust in efficacy is critical.
by mperham 5y ago
What's the alternative? Allow snakeoil? Now insurance has to cover it, incentivizing the creation of more ineffective drugs? Trust in efficacy is critical.
- jcims 5y agoWith cancer drugs at least, efficacy trials are regularly scoped to a fairly narrow portion of the patient population along things like the presence of specific mutations, whether those mutations are germline or somatic, previous treatment types administered and staging. Efficacy found for one combination of the above generally isn’t seen as transitive to the rest. The solution now seems to be to simply not allow that medication to be used if the patient doesn’t match the parameters of the trial. Some portion of those people then die because the current ‘standard of care’ is the same toxic shit they have been pumping i to veins for the past 30 years to little or no effect.