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I believe all vaccines, other than 3 Chinese ones with names starting with "Sino", target the spike protein and all indications I've seen have been that two dos

by Exmoor 5y ago

I believe all vaccines, other than 3 Chinese ones with names starting with "Sino", target the spike protein and all indications I've seen have been that two doses of different protein-targeting vaccines work well together. The bigger issue would be if "Original Antigenic Sin" [0] could impact the immune systems response, but that would be part of the testing prior to releasing the booster I'm sure. [0] https://en.wikipedia.org/wiki/Original_antigenic_sin https://en.wikipedia.org/wiki/Original_antigenic_sin

abystander 5y ago
> The bigger issue would be if "Original Antigenic Sin" [0] could impact the immune systems response presumably if this is an issue at all - it'd be because most people are "locked into" the spike protein as the original antigen, as opposed to those naturally infected and therefore carrying a immune repetoire against however many 10+ other proteins in sars-cov-2.