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Anyone knowledgeable on vaccines care to comment on how compatible a booster shot would likely be with other types of vaccine? While the first 2 shots were rel
by jacksonkmarley 5y ago
Anyone knowledgeable on vaccines care to comment on how compatible a booster shot would likely be with other types of vaccine?
While the first 2 shots were relatively close together the problems of brand-matching seem simpler than they would be many months later.
- Exmoor 5y agoI believe all vaccines, other than 3 Chinese ones with names starting with "Sino", target the spike protein and all indications I've seen have been that two doses of different protein-targeting vaccines work well together. The bigger issue would be if "Original Antigenic Sin" [0] could impact the immune systems response, but that would be part of the testing prior to releasing the booster I'm sure. [0] https://en.wikipedia.org/wiki/Original_antigenic_sin https://en.wikipedia.org/wiki/Original_antigenic_sin
- abystander 5y ago> The bigger issue would be if "Original Antigenic Sin" [0] could impact the immune systems response presumably if this is an issue at all - it'd be because most people are "locked into" the spike protein as the original antigen, as opposed to those naturally infected and therefore carrying a immune repetoire against however many 10+ other proteins in sars-cov-2.