Lots of similarities, one of the bigger differences is that Flask is standing on the shoulders of giants whereas Bottle is turtles all the way down. If a lack o

Lots of similarities, one of the bigger differences is that Flask is standing on the shoulders of giants whereas Bottle is turtles all the way down. If a lack of dependencies is a big deal to you, then Bottle wins, but given Python's packaging system, I don't see situations where that would matter a lot.