3 ms·
The data does not show that it works, and it was on a very specific sample (pre-alzheimers or early Alzheimer's). The drug costs $50k so they are profiting from
by jmcgough 5y ago
The data does not show that it works, and it was on a very specific sample (pre-alzheimers or early Alzheimer's). The drug costs $50k so they are profiting from desperate people.
And yes, it can make things worse:
"Most patients with AD (up to 75 percent) have a specific gene, called apolipoprotein E (APOE) ε4 allele; having this particular gene places a person at great risk of developing Alzheimer’s disease. Unfortunately, when AD patients with the APOE4 gene are given drugs like Aduhelm they are much more likely to develop brain edema and cerebral microhemorrhages. Indeed, in the BIOGEN trials, almost 50 percent of the APOE4 patients developed brain edema and hemorrhaging. In addition, these symptoms were accompanied by malignant hypertension and epileptic seizures."