2 ms·
It's also been linked to gingivitis: https://www.newsweek.com/dementia-gum-disease-alzheimers-linked-gingivitis-1301552 https://www.newsweek.com/dementia-gum-d
by callmeal 5y ago
It's also been linked to gingivitis:
https://www.newsweek.com/dementia-gum-disease-alzheimers-linked-gingivitis-1301552 https://www.newsweek.com/dementia-gum-disease-alzheimers-lin...
DNA tests on three brains with Alzheimer's disease and six healthy brains also had the gene associated with P. gingivalis in their tissue. The team also examined the cerebrospinal fluid and saliva of 10 patients believed to have Alzheimer's disease, and found the P. gingivalis gene hmuY in seven, and P. gingivalis itself in all of them.
And in an experiment on mice, those dosed with gingipains had higher levels of the hallmark Alzheimer's protein, amyloid beta, and greater damage to their neurons than those who didn't. What's more, when mice were treated with a drug blocking the enzymes, the neurodegeneration stopped.
...
However, he said the study was limited because the team has not yet determined if different strains of P. gingivalis are more virulent than others in causing brain infection. "This remains an area of active investigation," he said.
- fighterpilot 5y agoIt's also been linked to HSV-1