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Could there also be a sugar connection? Alzheimer's is referred to as "Type 3 Diabetes" where insulin resistance plays a role in a person developing the symptom

Could there also be a sugar connection? Alzheimer's is referred to as "Type 3 Diabetes" where insulin resistance plays a role in a person developing the symptoms. Do the populations of richer countries consume less sugar per head than poorer nations?

SturgeonsLaw 5y ago
Quite the opposite, per capita sugar consumption in developed countries is over 50% higher than developing countries, and 300% that of the least developed countries (35.5kg vs 21.6kg vs 11.4kg per person per year) https://www.oecd-ilibrary.org/docserver/agr_outlook-2015-table135-en.pdf?expires=1625222668&id=id&accname=guest&checksum=4D9B8392075F275DC0357ADAFAF37615 https://www.oecd-ilibrary.org/docserver/agr_outlook-2015-tab...
- tsjq 5y ago
  Wow! That's lot of opportunities for selling high-margin sugary drinks and snacks to the Billions of hungry people in least developed countries.
callmeal 5y ago
It's also been linked to gingivitis: https://www.newsweek.com/dementia-gum-disease-alzheimers-linked-gingivitis-1301552 https://www.newsweek.com/dementia-gum-disease-alzheimers-lin... DNA tests on three brains with Alzheimer's disease and six healthy brains also had the gene associated with P. gingivalis in their tissue. The team also examined the cerebrospinal fluid and saliva of 10 patients believed to have Alzheimer's disease, and found the P. gingivalis gene hmuY in seven, and P. gingivalis itself in all of them. And in an experiment on mice, those dosed with gingipains had higher levels of the hallmark Alzheimer's protein, amyloid beta, and greater damage to their neurons than those who didn't. What's more, when mice were treated with a drug blocking the enzymes, the neurodegeneration stopped. ... However, he said the study was limited because the team has not yet determined if different strains of P. gingivalis are more virulent than others in causing brain infection. "This remains an area of active investigation," he said.
- fighterpilot 5y ago
  It's also been linked to HSV-1

SturgeonsLaw 5y ago

Quite the opposite, per capita sugar consumption in developed countries is over 50% higher than developing countries, and 300% that of the least developed countries (35.5kg vs 21.6kg vs 11.4kg per person per year) https://www.oecd-ilibrary.org/docserver/agr_outlook-2015-table135-en.pdf?expires=1625222668&id=id&accname=guest&checksum=4D9B8392075F275DC0357ADAFAF37615 https://www.oecd-ilibrary.org/docserver/agr_outlook-2015-tab...

tsjq 5y ago
Wow! That's lot of opportunities for selling high-margin sugary drinks and snacks to the Billions of hungry people in least developed countries.

callmeal 5y ago

It's also been linked to gingivitis: https://www.newsweek.com/dementia-gum-disease-alzheimers-linked-gingivitis-1301552 https://www.newsweek.com/dementia-gum-disease-alzheimers-lin... DNA tests on three brains with Alzheimer's disease and six healthy brains also had the gene associated with P. gingivalis in their tissue. The team also examined the cerebrospinal fluid and saliva of 10 patients believed to have Alzheimer's disease, and found the P. gingivalis gene hmuY in seven, and P. gingivalis itself in all of them. And in an experiment on mice, those dosed with gingipains had higher levels of the hallmark Alzheimer's protein, amyloid beta, and greater damage to their neurons than those who didn't. What's more, when mice were treated with a drug blocking the enzymes, the neurodegeneration stopped. ... However, he said the study was limited because the team has not yet determined if different strains of P. gingivalis are more virulent than others in causing brain infection. "This remains an area of active investigation," he said.

fighterpilot 5y ago
It's also been linked to HSV-1