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How do vaccines with live parasites work? Does attenuation somehow guarantee that the live parasites won't replicate to the point of becoming a full-on infecti
by cwkoss 5y ago
How do vaccines with live parasites work? Does attenuation somehow guarantee that the live parasites won't replicate to the point of becoming a full-on infection?
Can these vaccines only be used on patients with healthy immune systems, and those with weakened immune systems have the potential for cascading replication and full infections?
- tmp538394722 5y agoThe article mentions that the parasites are treated if they infect the blood or liver… So I guess they are monitoring the vaccinated closely. Honestly sounds a bit touchy.
- lucioperca 5y agoThere are other vaccines such as the polio (the one which was swallowed) which had a similar mechanism. You could even infect others with it (which has benefits for herd immunity). But the chances of vaccine-associated paralytic poliomyelitis was extremely low 1:2.700.000 (it was not given to people with immunity defects).
- canadianfella 5y agoWhy “but”?
- passivate 5y agoAs per their publication, they simultaneously give you anti-malaria medication in addition to the sporozoites. Its called chemoprophylaxis vaccination. (Just learned of it today)