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A library[1] small molecule drug that reverses dementia by acting on a calcium channel based on mouse data? Press X to Doubt [1] https://www.tocris.com/produc
by frisco 5y ago
A library[1] small molecule drug that reverses dementia by acting on a calcium channel based on mouse data?
Press X to Doubt
[1] https://www.tocris.com/products/sak-3_6239 https://www.tocris.com/products/sak-3_6239
- wombatmobile 5y agoDoubt is healthy and free but it doesn't get you anywhere. If you evaluate the mechanism they explain, your prognosis will be better informed. Really the size of the molecule is neither here nor there. It's the therapeutic application that counts. > SAK3 enhanced the proteasome activity via CaMKII activation Consider why that might be effective. It is explained clearly in their AD paper abstract. https://pubmed.ncbi.nlm.nih.gov/3060144/ https://pubmed.ncbi.nlm.nih.gov/3060144/