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Thanks, this is quite re-assuring since I am worried about prions as well. Could you please suggest a link for me to further educate myself on how unlikely thi
by seaman1921 5y ago
Thanks, this is quite re-assuring since I am worried about prions as well.
Could you please suggest a link for me to further educate myself on how unlikely this is ?
- XorNot 5y agoThis isn't bad: https://www.scientificamerican.com/article/what-is-a-prion-specifica/ https://www.scientificamerican.com/article/what-is-a-prion-s... The basic punchline is that while prion diseases are terrifying, there's not a lot of them and they are quite specific - you have to have a protein which is already able to adopt that conformational structure, and it has to be a protein we already make natively, as prions only work with what's there. We are probably still missing part of the picture as well: i.e. the prion diseases which cause problems are brain diseases, we don't see the same issue with other tissues. It would be difficult to actually induce a prion disease in someone via genetic vaccine in the first place, since prion's notably don't have a genetic component - and in the case of vCJD the infectious and benign protein sequences are the same (i.e. the coding is already something we carry, they're conformational jumps).
- seaman1921 5y ago> the coding is already something we carry, they're conformational jumps Aha, this is helpful. And I believe mRNAs are not known to trigger these conformational jumps. Another fact-check article supporting your statement: https://www.reuters.com/article/fact-check-no-evidence-that-pfizers-covi-idUSL1N2MZ382 https://www.reuters.com/article/fact-check-no-evidence-that-...