3 ms·
What happens to the unactivated mRNA in that case? I was under the impression that it was typically the actual use of the mRNA by the ribosomes that broke them
by monocasa 5y ago
What happens to the unactivated mRNA in that case? I was under the impression that it was typically the actual use of the mRNA by the ribosomes that broke them down generally, but I could be off base there.
- gus_massa 5y agoThe same mRNA can be used by multiple ribosomes. More info and "photos": https://biology.stackexchange.com/questions/54752/can-mrna-be-used-by-ribosomes-more-than-once https://biology.stackexchange.com/questions/54752/can-mrna-b...
- monocasa 5y agoSure, it isn't destroyed immediately and the mRNA is used multiple time, but that's still ultimately the ribosomes damaging the mRNA from use. My question is around how they break down if there aren't ribosomes involved (ie. if the capsules above aren't opened because they weren't exposed to the light trigger).
- sudosysgen 5y agoEventually the capsule will break down, be filtered out or be destroyed by the immune system and any RNA left will be broken down by RNAse.
- gus_massa 5y agoMore info about RNA destruction and RNAse https://en.wikipedia.org/wiki/Ribonuclease https://en.wikipedia.org/wiki/Ribonuclease