10 ms·
> A key principle of DHCA is total inactivation of the brain by cooling, as verified by "flatline" isoelectric EEG, also called electrocerebral silence (ECS). I
by goldenkey 5y ago
> A key principle of DHCA is total inactivation of the brain by cooling, as verified by "flatline" isoelectric EEG, also called electrocerebral silence (ECS). Instead of a continuous decrease in activity as the brain is cooled, electrical activity decreases in discontinuous steps. In the human brain, a type of reduced activity called burst suppression occurs at a mean temperature of 24 °C, and electrocerebral silence occurs at a mean temperature of 18 °C.[32] The achievement of measured electrocerebral silence has been called "a safe and reliable guide" for determining cooling required for individual patients,[33] and verification of electrocerebral silence is required prior to stopping blood circulation to begin a DHCA procedure.[34]
Thank you for the link. Is "measured electrocerebral silence" a measure of zero electrical current in the brain? Or just close to it?
- nynx 5y ago> Electrocerebral inactivity (ECI), or electrocerebral silence (ECS), is defined as no cerebral activity over 2 µV using a montage that uses electrode pairs at least 10 cm apart with interelectrode impedances < 10,000 ohms and >100 ohms. https://www.medscape.com/answers/1140075-177597/how-is-electrocerebral-inactivity-defined-on-eeg https://www.medscape.com/answers/1140075-177597/how-is-elect...
- goldenkey 5y agoVery interesting, this changes my understanding quite a bit. Do you know if these patients had any short term memory effects? If not, this would imply that the brain is JITing structure almost immediately from events... that's mindblowing.