The European datasets are essentially useless because they lack diversity. So you cannot make any generalisations. You need a highly diverse dataset to start lo

The European datasets are essentially useless because they lack diversity. So you cannot make any generalisations. You need a highly diverse dataset to start looking for patterns of expression in subgroups to draw any meaningful conclusions. Just to add to this. I work adjacent to a lab developing forensic kits for black South African populations. The kits developed in the US and Europe don't really work on Xhosa or Zulu populations. This is incredibly important due to the high levels of gender violence in the country.