3 ms·
Well, you're sure to get something with an inactivated viral particle. But you're not sure to get a usefully efficient protection from exposure to it. The prob
by superkuh 5y ago
Well, you're sure to get something with an inactivated viral particle. But you're not sure to get a usefully efficient protection from exposure to it.
The problem with inactivated viral particles is the inactivation process, neccessarily, breaks the proteins and cause them to be liable to take up non-realistic shapes. When your immune system trains on the non-realistic shape the antibodies don't neutralize as well. See the sinovac inactivated sars-cov-2 vaccine for an example of this type of vaccine not working out (ie, <50% efficient).