The first author of linked paper is (in)famous for being highly prolific and having a large number of retractions: https://en.wikipedia.org/wiki/Bharat_Aggarwal

The first author of linked paper is (in)famous for being highly prolific and having a large number of retractions: https://en.wikipedia.org/wiki/Bharat_Aggarwal#Scientific_misconduct https://en.wikipedia.org/wiki/Bharat_Aggarwal#Scientific_mis... http://retractiondatabase.org/RetractionSearch.aspx?AspxAutoDetectCookieSupport=1#?AspxAutoDetectCookieSupport%3d1%26auth%3dAggarwal%252c%2bBharat%2bB http://retractiondatabase.org/RetractionSearch.aspx?AspxAuto... A more recent skeptical review of curcumin (https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.6b00975 https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.6b00975) labels it an "invalid metabolic panacea" and a "pan-assay interference compound", arguing that it has properties that lead to a lot of false positives in initial activity screening that don't pan out: No double-blinded, placebo controlled clinical trial of curcumin has been successful.