> doses up to 100-fold higher than those approved for use in humans. Drugs are approved according to their use. If they have multiple uses, they will have mul

> doses up to 100-fold higher than those approved for use in humans. Drugs are approved according to their use. If they have multiple uses, they will have multiple approved dosages. Someone with sudden sensorineural hearing loss might be prescribed 60mg of prednisone per day, while someone who takes it for rheumatoid arthritis will take only 10 mg per day. One dose is six times the other dose. Both are safe, and both are approved. It's also necessary to consider the drug's therapeutic index. Therapeutic index is a ratio that measures the difference between the effective dose of a drug and its lethal dose. [1] NIH data indicates that administering ivermectin (at these "100-fold higher" dosages) to treat COVID-19 is no more dangerous than placebo. [2] 1. https://en.wikipedia.org/wiki/Therapeutic_index https://en.wikipedia.org/wiki/Therapeutic_index 2. https://pubchem.ncbi.nlm.nih.gov/compound/ivermectin#section=Toxicity https://pubchem.ncbi.nlm.nih.gov/compound/ivermectin#section...