3 ms·

From what I understand, it's the anti-inflammatory piece of Ivermectin that can help with covid because, apparently, the respiratory issue with covid is not cau

• DoreenMichele 5y ago
  Antiinflammatories are generally useful against all kinds of things. Inflammation is a common side effect of infection. I find that answer unsatisfactory. If "it's an anti-inflammatory!" is The Answer, there are lots of antiinflammatories out there.
  • ds206 5y ago
    Here, try this video https://youtu.be/kSWjl-JOIqs https://youtu.be/kSWjl-JOIqs
    • ds206 5y ago
      Sorry, that clip doesn't talk about what I thought it did. I watched the whole 2.5 video before it was censored/taken down from YouTube and somewhere in there they talk about why they think Ivermectin is effective (assuming it is). The full video can be watched here: https://odysee.com/@BretWeinstein:f/COVID-Ivermectin-and-the-Crime-of-the-Century-DarkHorse-Podcast-with-Pierre-Kory-Bret-Weinstein https://odysee.com/@BretWeinstein:f/COVID-Ivermectin-and-the...
  • rolph 5y ago
    ivermectin effects chloride channels in neurons of parasites. in mammals ivermectin effects nuclear transport protiens responsible for mediating signal peptide transport to the nucleus. the in vivo concentration corresponding to EC50 was reported in the range of 2. to 5. micromolar this is a very problematic dose, for humans; this drug targets host, and pathogen, albeit by different mechanisms. https://en.wikipedia.org/wiki/Ivermectin https://en.wikipedia.org/wiki/Ivermectin https://en.wikipedia.org/wiki/COVID-19_misinformation#Ivermectin https://en.wikipedia.org/wiki/COVID-19_misinformation#Iverme... https://en.wikipedia.org/wiki/COVID-19_drug_repurposing_research#Ivermectin https://en.wikipedia.org/wiki/COVID-19_drug_repurposing_rese...
    • DoreenMichele 5y ago
      ivermectin effects chloride channels in neurons of parasites. in mammals ivermectin effects nuclear transport protiens responsible for mediating signal peptide transport to the nucleus. So that first statement makes some kind of sense to me. That second one doesn't quite parse for me. Can anyone kind of explain that in layman's terms? (Thanks to everyone who has indulged my curiosity. I'm just trying to better understand the piece that most directly answers my question here.)
      • rolph 5y ago
        the nucleus of a eukaryotic; mammalian cell [a.k.a. humans] is surrounded by a membrane, this membrane has a number of protiens studded into it, some are channels, others "do backflips" to transport things across the nuclear membrane. why do this ?.... protiens are made outside of the nucleus and must be inserted into the nucleus. some of these are structural protiens, others are enzymes, and others are signals to the nucleus to switch operations for the time being, constantly chasing after homeostasis. Ivermectin disrupts signal transport protien, and becomes cytotoxic, in higher doses due to its effect on the genetic expression signaling system. [ADNDM] the claim is that CoV2019 infects a cell then produces a protien that enters the host nucleus and ultimately modulates interferon production, by the infected cell, and that Ivermectin can disrupt this. when covid imports a specific protien this lowers the signal the infected cell attempts to give surrounding cells that there is an invader, and to harden up molecular defenses. the problem is that the cell relies on this nuclear transport of signals for proper functioning, so you cant just block it, and expect the host to be spared cytotoxic effect.
        • DoreenMichele 5y ago
          Thank you.