The coarseness of pharmacological dosing: Right now, if the average effective dose is 10mg, doc just gives you 10mg. Often pharmacies can only provide multipl

The coarseness of pharmacological dosing: Right now, if the average effective dose is 10mg, doc just gives you 10mg. Often pharmacies can only provide multiples of this. People can have very dramatic differences in drug metabolism and tolerance, so this 'one size fits all' attitude is very coarse. I think it would be much better for certain medications, particularly ones that are taken over longer periods of time, to be titrated more carefully: - First dose should be <= 1/10th effective dose to check for hypersensitivity or allergies - Early doses should gradually titrate up - patient has no tolerance, and so early doses will have more effect. Titration should watch for both whether therapeutic effect is being achieved and whether side effects occur. - If therapeutic effect is achieved, stop increasing the dose. Possibly slowly reduce the dose until therapeutic effects are insufficient and then step up a little but in order to minimize side effects. - If side effects are too severe and no therapeutic effects are found, look for another drug. * This could be counterproductive for certain medications, like antibiotics or drugs with atypical dose response curves I think the main hurdle is that custom-dosing medications is expensive to do currently. Also requires an ability to quickly detect and react to whether therapeutic or side effects are occurring, which is also expensive and has patient compliance issues.