4 ms·

It's been found that through reverse transcriptase it's actually possible for the RNA from covid infections to be integrated into the genes: https://pubmed.ncbi

• klmr 5y ago
  These findings are probably spurious and caused by artefacts of their methods rather than real. In particular, the preprint you’ve linked to had glaring methodological flaws [1]. A revised version of the article [2] has addressed some, but notably not all of these flaws. More importantly, though, all the paper shows is that under specific lab conditions (which are distinct from conditions in living cells!), viral RNA might integrate into the host genome (subject to the caveats about artefacts). In particular, it requires active retrotransposons [3], which are elements that are inactive in cells in the body. Unless a virus brings its own retrotransposon (and SARS-CoV-2 doesn’t), it can’t integrate into the host genome. But even if SARS-CoV-2 did, they mRNA vaccine definitely doesn’t include a retrotransposon. [1] https://www.biorxiv.org/content/10.1101/2021.03.05.434119v1 https://www.biorxiv.org/content/10.1101/2021.03.05.434119v1 [2] https://www.pnas.org/content/118/21/e2105968118 https://www.pnas.org/content/118/21/e2105968118 [3] https://twitter.com/GeneticsMike7/status/1404927629812240388 https://twitter.com/GeneticsMike7/status/1404927629812240388