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But, after 50+ years of rising sunscreen use, there's essentially no data showing more sunscreen use reduces skin cancer. Sunscreen definitely prevents sunburn
by gojomo 5y ago
But, after 50+ years of rising sunscreen use, there's essentially no data showing more sunscreen use reduces skin cancer.
Sunscreen definitely prevents sunburns, and almost certainly delays visible skin aging/weathering. Those may be enough benefits for some people.
But the people/populations using more sunscreen are also having more skin cancer. Some theories compatible with these observations are:
• While preventing sunburn pain, sunscreen doesn't prevent the actual cancer-causing skin damage - and thus by allowing more time to be spent in the sun, actually worsened skin cancer rates. (This may have especially been a problem for the 1960s-1990s, when it was thought that only sunburn-causing UVB contributed to skin cancer - so sunscreens only blocked UBV. That encouraged increased exposure to the mostly-unblocked UVA, now understood as an equal contributor to skin cancer. More recent sunscreens block UVA as well.)
• Known carcinogens commonly used in sunscreens, or present as contaminants, are actually causing increased rates of skin cancer.
Anyone whose true worry is skin cancer should use shade & limited times of exposure - not sunscreens. (Ensuring a spaced-repetition of gradually-increasing exposure, to develop a natural tan without ever reaching a peeling burn, is also likely naturally protective against skin cancer.)
Further, while endogenous Vitamin D production relies on sun exposure, and low Vitamin D is correlated with health problems, oral Vitamin D supplementation may not replace all the benefits of sun exposure.
Generally, large population studies show positive effects of moderate sun exposure on many health outcomes, including overall longevity, heart disease, and non-skin cancers. Meanwhile, Vitamin D supplementation studies have usually not found that such supplementation alone reverses the correlations of many diseases with low Vitamin D. Thus, Vitamin D may not be the only mechanism by which sun's benefits are achieved.
So rigorous sun-exposure-minimization, even if it does reduce (often benign or increasingly survivable) skin cancers, may increase overall mortality through higher heart disease & other cancers. (Your HHS report mentions 9,000 skin melanoma deaths per year. There are 650,000 heart-disease deaths and 600,000 other cancer deaths.)
Get sun. Use shade, clothing, & timing to ensure it's not so much sun that you peel. Use sunscreen sparingly, only when you can't moderate sun exposure other ways.
- seattle_spring 5y agoCan you provide some peer reviewed sources for your claims? Your whole comment reads like that thoroughly debunked "scientists blow the lid off of sunscreen" [1] article that was going around a few years back. [1] https://millerfamilydermatology.com/sunscreen-myth/ https://millerfamilydermatology.com/sunscreen-myth/
- gojomo 5y agoHere's a good recent overview of reasons to doubt the efficacy of sunscreen against fatal skin cancers: https://www.outsideonline.com/2380751/sunscreen-sun-exposure-skin-cancer-science https://www.outsideonline.com/2380751/sunscreen-sun-exposure... (Most recently discussed on HN at https://news.ycombinator.com/item?id=23086211 https://news.ycombinator.com/item?id=23086211) Similar doubts have existed for decades – here's a 1993 variant reporting some of the trends that already didn't add up, back then: https://www.motherjones.com/politics/1993/05/melanoma-sunscreen-use/ https://www.motherjones.com/politics/1993/05/melanoma-sunscr... Another branch reply provides more sources about sunscreen chemicals & sun-longevity correlations: https://news.ycombinator.com/item?id=27520144 https://news.ycombinator.com/item?id=27520144
- 49531 5y ago> • Known carcinogens commonly used in sunscreens, or present as contaminants, are actually causing increased rates of skin cancer. I am curious to see a citation for this claim. > Generally, large population studies show positive effects of moderate sun exposure on many health outcomes, including overall longevity, heart disease, and non-skin cancers. Meanwhile, Vitamin D supplementation studies have usually not found that such supplementation alone reverses the correlations of many diseases with low Vitamin D. Thus, Vitamin D may not be the only mechanism by which sun's benefits are achieved. I am also curious to see these studies, and wonder if they control for other variables like physical activity. I think it's an incorrect framework to say that you have to choose between skin cancer and heart disease, you can avoid both through different lifestyle choices.
- baumandm 5y agoHere's a recent HN discussion of a study that found benzene in 27% of tested sunscreen samples: https://news.ycombinator.com/item?id=27292387 https://news.ycombinator.com/item?id=27292387
- gojomo 5y agoMany intentional functional ingredients in sunscreens are known carcinogens and absorbed at levels beyond any safety testing: https://www.webmd.com/skin-problems-and-treatments/news/20200121/fda-skin-absorbs-dangerous-sunscreen-chemicals https://www.webmd.com/skin-problems-and-treatments/news/2020... Contamination of sunscreens with common dangerous byproducts of industrial processes like benzene is common: https://www.washingtonpost.com/lifestyle/wellness/benzene-sunscreen-safe-carcinogen-/2021/06/04/33723cb6-c55f-11eb-9a8d-f95d7724967c_story.html https://www.washingtonpost.com/lifestyle/wellness/benzene-su... By comparison, shade contains no carcinogens. Sun exposure correlated with longer life (even while also being correlated with more cancer deaths!): https://www.health.harvard.edu/blog/heres-something-unexpected-sunbathers-live-longer-201606069738 https://www.health.harvard.edu/blog/heres-something-unexpect... An earlier broad survey also finding natural sun exposure decreasing all-cause mortality (but not use of tanning beds, despite similar effects on Vitamin D production, again suggesting D-supplements alone don't replicate the sun): https://cebp.aacrjournals.org/content/20/4/582 https://cebp.aacrjournals.org/content/20/4/582 I'd agree, it is hard to disentangle these correlations with things like general levels of outdoor activity and socializing. But even so: if people who are healthy for other reasons tend to spend more time outside in sun, maybe it'd be a good idea to join them, & perhaps absorb their other habits as well, rather than live in fear of the sun? (Maybe even the sun is damaging on many levels, but the other benefits of activities inherently done more under the sun offset those effects, even if just via mood/optimism?) I'd say instead that it's an incorrect framework to embrace an illusion of total control "through different lifestyle choices" without tradeoffs. Every activity has a mix of risks and benefits. Certain vigorous activities with a higher risk of accidental death may deliver other fitness and social benefits. If an extra 5 hours of sun every week doubles melanoma death risk, but reduces cardio/cancer death risk just 1%, that sun would still be a net-mortality benefit. Such tradeoffs are real & everywhere. Trying to engineer both benefits – "can I do everything other healthy people do usually do outdoors indoors? can I find the least-dangerous sunscreen? will vitamin D supplments, perhaps with a bunch of other diet changes, simulate the sun's benefits?" – also includes costs, in research time, psychological focus, neurotic behaviors, etc, for diminishing returns.
- psychometry 5y ago>But the people/populations using more sunscreen are also having more skin cancer Um, you missed the most obvious explanation (assuming that's even true): People who have an elevated risk of skin cancer (due to geographic location and/or skin type) are likely to use more sunscreen for that very reason, but despite their sunscreen use they're still at an elevated risk of cancer because sunscreen cannot eliminate all risk. It's really no different than saying that people who are receiving more IV chemotherapy are also dying of cancer more often than people who aren't.
- nomel 5y agoThe majority of my family has had skin cancer (we don't tan, we burn). It's usually in places you can't put sunscreen, like eyelids, close to the lips, etc.
- gojomo 5y agoThis sort of confounder is common, but we have in the US a population that, over the decades, is (pre-exposure) no more pale/susceptible-to-burns. The public has been bombarded for decades with the health message to avoid the sun, and a deep tan has become less fashionable. (My younger friends, especially, treat minimizing tans/exposure as an almost religious obligation.) Sunscreens have broadened the wavelengths they block – they used to mostly skip UVA, thinking it harmless – and upped their SPF factors. (In the 1980s, I recall SPF15 as the max - now it's SPF30, SPF80, SPF100.) Sales & usage of sunscreen keep growing. But melanoma case rates are still on a long-term rising trend. Deaths have finally improved slightly in the last few years - likely from earlier detection & better treatment. If the population's generally the same, but slathering on far more sunscreen every decade – but cases still go up & mortality barely budges – there's little hint of effective protection.
- lotsofpulp 5y ago> If the population's generally the same, but slathering on far more sunscreen every decade – but cases still go up & mortality barely budges – there's little hint of effective protection. It is not so simple to come to this conclusion. You would have to establish that time spent in sun per person has not gone up, that per person use of sunscreen (good quality sunscreen) has gone up by a measurable amount, that it is being used properly, and the cancer is happening on areas where sunscreen was used. In addition, you would have to control for people living longer. Note that the US population in less sunny and cold areas (Midwest and Northeast) has stalled for 3 decades compared to explosive growth in population in the South and West (sunny, warm areas).
- wahern 5y ago> But, after 50+ years of rising sunscreen use, there's essentially no data showing more sunscreen use reduces skin cancer. 50% reduction in melanoma: https://pubmed.ncbi.nlm.nih.gov/21135266/ https://pubmed.ncbi.nlm.nih.gov/21135266/ 40% reduction in squamous cell carcinoma: https://pubmed.ncbi.nlm.nih.gov/10475183/ https://pubmed.ncbi.nlm.nih.gov/10475183/ See, generally, https://www.skincancer.org/skin-cancer-information/skin-cancer-facts/ https://www.skincancer.org/skin-cancer-information/skin-canc... Perhaps you were thinking of basal cell carcinoma, the most common type of skin cancer. There does seem to be a lack of experimental evidence wrt BCC: https://www.hindawi.com/journals/jsc/2012/480985/ https://www.hindawi.com/journals/jsc/2012/480985/ The skincancer.org FAQ conspicuously skips around that hole.
- gojomo 5y agoMelanomas are the skin cancer of primary concern. Your "50% reduction in melanoma" link is interesting, but pretty small & low-powered - and followup comments (such as https://ascopubs.org/doi/10.1200/JCO.2011.35.5727 https://ascopubs.org/doi/10.1200/JCO.2011.35.5727) highlight potential major problems in study design. For example: • Study wasn't originally designed to detect effect on melanomas - that endpoint was added later. (This, alone, suggests possible p-hacking.) • Instructions thus didn't even direct sunscreen application to the areas melanomas most often occur. Yet, at followup both control & intervention groups had a disproportionate number of melanomas in exactly the areas where application had been directed (and most applied, by self-reports, in both groups). As the commenters note, this is actually consistent with the theory that sunscreen encourages overexposure moreso than it protects. • Small changes in arbitrary study choices - like to what extent back/leg melanomas were considered (when those areas weren't part of the encouraged sunscreen-application area), or whether a 1, 2, or 4 year exclusion of early events applied – remove the claim of 'significance', suggesting a very fragile result. If the protective relationship of sunscreen were real, it'd have lots of studies with robust results. Or, the massive increases in recent decades in SPF factors, sunscreen purchasing/use, and sun-avoidance messaging and practice would've reduced melanoma rates. Instead, melanoma rates keep going up. To me, that's far more powerful evidence than a repurposed study with 11 more melanomas (but fewer invasive ones!) in a slightly-less-sunscreen-using control group. The squamous study is also murky, though not as much. Its abstract notes, "There were no significant differences in the incidence of first new skin cancers between groups randomly assigned daily sunscreen and no daily sunscreen (basal-cell carcinoma 2588 vs 2509 per 100,000; rate ratio 1.03 [95% CI 0.73-1.46]; squamous-cell carcinoma 876 vs 996 per 100,000; rate ratio 0.88 [0.50-1.56])." The same number of people got new skin cancers in both groups! It's only the secondary count of tumours where the control group had more. I'm unsure that's an important protective effect. But going back, I really should have said: "no data showing more sunscreen reduces deadly skin cancers". There's a reasonable amount of evidence sunscreen reduces various kinds of mild skin-tumours, much like the obvious-to-the-naked-eye effectiveness against sunburns. But for melanomas/death-by-skin-cancer – the top worry of most sunscreen users – any effect is either very weak, non-existent, or possibly even inverse.
- Spooky23 5y agoI don't know why your comment is being voted down, it's a reasonable one, although I disagree with parts of it. Depending on your skin type, "Get Sun" may not be good advice, especially if you make a mistake. A single significant sunburn in your teens significantly increases your lifetime risk of getting a skin cancer, of which melanoma is just one. My wife developed melanoma and is in remission. She is fair skinned and very sun-cautious -- typically using clothing as a primary barrier with sunscreen. Like anything risk assessment and risk tolerance is key and difficult to assess. Another factor to consider is that mortality doesn't always tell the story. Some surgical procedures introduce significant scarring. Treatment for a stage-2 melanoma will often include removing lymph nodes, which introduce other complications. Also be careful, as past diagnoses of cancers were not great. That melanoma that moved into an organ may not have been classified correctly in 1960. Personally, my advice is go outside, dress appropriately and use a mineral-based sunscreen if you're going to be out for more than a half hour or so. Don't go swimming at solar noon. Don't tan. Wear a rash-guard at the beach. Wear a hat at the ballgame.
- treeman79 5y agoLong term sun exposure vs shade. Curious if sunscreen would have helped https://www.huffingtonpost.ca/2012/06/06/bill-mcelligott-sun-damage_n_1573546.html https://www.huffingtonpost.ca/2012/06/06/bill-mcelligott-sun...
- cactus2093 5y agoThere is evidence that bad (peeling) sunburns as a child are a major risk factor in melanoma. That is never going to be feasible to study in a randomized control trial, in addition to the study taking 40 years to complete it would be unethical to burn children that badly on purpose. Randomized control trials on seatbelts saving lives are also hard to find for the same reason but that doesn’t mean they don’t work. Also, as anyone who burns easily will be well aware, sunscreen is almost impossible to use properly in the real world. You need to cover every inch of your skin and reapply every 60-90 minutes and make sure not to let it wash off by going in the water too soon or sweating too much, make sure not to rub it off with clothing or towels, etc. The first part of your advice makes sense in light of this - shade and clothing are much more practical ways to stay safe if you’re outdoors all day and burn easily. “Use sunscreen sparingly” is just stupid advice to be giving though. There is much more evidence to it helping than doing any harm.