3 ms·
https://www.biorxiv.org/content/10.1101/2020.12.12.422516v1.full.pdf https://www.biorxiv.org/content/10.1101/2020.12.12.422516v1....
by informatimago 5y ago
https://www.biorxiv.org/content/10.1101/2020.12.12.422516v1.full.pdf https://www.biorxiv.org/content/10.1101/2020.12.12.422516v1....
- spadez 5y agoAlso asked about this here, but didn't get a lot of responses https://news.ycombinator.com/item?id=27495352 https://news.ycombinator.com/item?id=27495352
- gus_massa 5y agoFrom the preprint: > Plasmid for HIV-1 reverse transcriptase expression: pCMV-dR8.2 dvpr was a gift from 189 Bob Weinberg (Addgene plasmid # 8455 ; http://n2t.net/addgene:8455 http://n2t.net/addgene:8455 ; > SARS-CoV-2 RNA can be reverse-transcribed and integrated into the human genome in cells overexpressing a reverse transcriptase It's not my area, so I'm not sure, but I think that they added too much reverse transcriptase in an unrealistic concentration. (They are using a reverse transcriptase, that is an important enzyme for HIV, but it's not present in coronavirus and is not present in the vaccine.) I think it's not totally impossible that the mRNA is copied to the ADN of the cell, it's just an unrealistic scenario to be worried about.