What computer models? I can imagine that it is possible to predict some already known toxicological mechanisms for similar molecules. But we're certainly not ev

What computer models? I can imagine that it is possible to predict some already known toxicological mechanisms for similar molecules. But we're certainly not even close to anywhere where we could predict unknown toxicological interactions. And in vitro tests are very limited in that area. Of course they're still done and useful, but they can't replace animal tests. And testing on paid volunteers is still ethically problematic, you're targeting pretty desperate people if you remove animal experiments which could detect toxic compounds.