The article doesn’t actually talk about it in any meaningful way. They talk about it in a statistical fashion: most animal studies are underpowered, most don’t

The article doesn’t actually talk about it in any meaningful way. They talk about it in a statistical fashion: most animal studies are underpowered, most don’t publish, etc. And sure, I think we can all agree that nobody should be doing useless experiments, whether on animals or not. But that in no way proves the article’s argument, and it hardly even supports it. Are we going to test out new CRISPR therapeutic delivery systems in humans? We don’t have a non-living system that replicates a circulatory system, an immune system, and a liver. If the author has a suggestion for how to do things like this safely and effectively without animals, I didn’t hear it.