Original article (with link to PDF): https://advances.sciencemag.org/content/7/24/eabe4577 https://advances.sciencemag.org/content/7/24/eabe4577. I do not know

Original article (with link to PDF): https://advances.sciencemag.org/content/7/24/eabe4577 https://advances.sciencemag.org/content/7/24/eabe4577. I do not know much about testing mice in this study's context. In light of my unfamiliarity, I am astounded that up to 20mg/kg of morphine can be given to mice without fatally suppressing their respiratory drive! If I give a (human) patient even 1mg/kg, I am likely to kill them in absence of airway/respiratory support (not to mention their likely markedly reduced BP). Maybe I am misreading that which I am unfamiliar with. Fascinating, regardless!