5 ms·

Vit D deficiency strongly exaggerates the craving for and effects of opioids

34 points by fnord77 5y ago

WalterGR 5y ago
The original title should be used in submissions. In this case: "Vitamin D deficiency may increase risk for addiction to opioids and ultraviolet rays" But that's 4 characters too long. Here's a slightly modified title that both closely resembles the original and fits within the limit: "Vitamin D deficiency may raise risk for addiction to opioids, ultraviolet rays"
- LZ_Khan 5y ago
  Addiction to ultraviolet rays? That's a new sentence for me.
  - rasz 5y ago
    Ganguro / Gyaru
  - webmaven 5y ago
    > Addiction to ultraviolet rays? That's a new sentence for me. Here's some background material on the subject: https://www.sciencedirect.com/science/article/abs/pii/S0733863508001058 https://www.sciencedirect.com/science/article/abs/pii/S07338... https://pubmed.ncbi.nlm.nih.gov/20545951/ https://pubmed.ncbi.nlm.nih.gov/20545951/ https://hms.harvard.edu/news/addicted-sun https://hms.harvard.edu/news/addicted-sun
- fnord77 5y ago
  they changed the title apparently after I submitted
btach 5y ago
Original article (with link to PDF): https://advances.sciencemag.org/content/7/24/eabe4577 https://advances.sciencemag.org/content/7/24/eabe4577. I do not know much about testing mice in this study's context. In light of my unfamiliarity, I am astounded that up to 20mg/kg of morphine can be given to mice without fatally suppressing their respiratory drive! If I give a (human) patient even 1mg/kg, I am likely to kill them in absence of airway/respiratory support (not to mention their likely markedly reduced BP). Maybe I am misreading that which I am unfamiliar with. Fascinating, regardless!
bricss 5y ago
How about? - Combining Aspirin with Cholecalciferol (Vitamin D3) – A Potential New Tool for Controlling Possum Populations https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0070683 https://journals.plos.org/plosone/article?id=10.1371/journal...

5 ms·

Vit D deficiency strongly exaggerates the craving for and effects of opioids

34 points by fnord77 5y ago

WalterGR 5y ago
The original title should be used in submissions. In this case: "Vitamin D deficiency may increase risk for addiction to opioids and ultraviolet rays" But that's 4 characters too long. Here's a slightly modified title that both closely resembles the original and fits within the limit: "Vitamin D deficiency may raise risk for addiction to opioids, ultraviolet rays"
- LZ_Khan 5y ago
  Addiction to ultraviolet rays? That's a new sentence for me.
  - rasz 5y ago
    Ganguro / Gyaru
  - webmaven 5y ago
    > Addiction to ultraviolet rays? That's a new sentence for me. Here's some background material on the subject: https://www.sciencedirect.com/science/article/abs/pii/S0733863508001058 https://www.sciencedirect.com/science/article/abs/pii/S07338... https://pubmed.ncbi.nlm.nih.gov/20545951/ https://pubmed.ncbi.nlm.nih.gov/20545951/ https://hms.harvard.edu/news/addicted-sun https://hms.harvard.edu/news/addicted-sun
- fnord77 5y ago
  they changed the title apparently after I submitted
btach 5y ago
Original article (with link to PDF): https://advances.sciencemag.org/content/7/24/eabe4577 https://advances.sciencemag.org/content/7/24/eabe4577. I do not know much about testing mice in this study's context. In light of my unfamiliarity, I am astounded that up to 20mg/kg of morphine can be given to mice without fatally suppressing their respiratory drive! If I give a (human) patient even 1mg/kg, I am likely to kill them in absence of airway/respiratory support (not to mention their likely markedly reduced BP). Maybe I am misreading that which I am unfamiliar with. Fascinating, regardless!
bricss 5y ago
How about? - Combining Aspirin with Cholecalciferol (Vitamin D3) – A Potential New Tool for Controlling Possum Populations https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0070683 https://journals.plos.org/plosone/article?id=10.1371/journal...