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how do you know what is produced and called "just mRNA" is the exact same kind of thing that is the mRNA in your body? You can test to verify that it has all th

by nsonha 5y ago

how do you know what is produced and called "just mRNA" is the exact same kind of thing that is the mRNA in your body? You can test to verify that it has all the characteristics of mRNA. However, you obviously can't 100% confirm that it does not have characteristics that is not in "natural" mRNA, since the list of characteristics mRNA does NOT have is infinite.

kaba0 5y ago
What do you mean produced? As in the pharmaceutical factory? You can quite literally have a look at it with an electron microscope, and there are trillion other ways to chemically verify that. Also, we can reprogram bacteria to manufacture any protein for us - molecular biology is very advanced. Why do you feel the need to question very basic “problems” that were more than certainly thought about and solved by the many experts working on it for decades? You can question whether the engineers of a car engine though of heat dissipation but you would find it sort of dumb, wouldn’t you?
- nsonha 5y ago
  > trillion other ways to chemically verify that Trillion? Did you not read what I said about being able to verify the behaviors you want and not the side effects you don't yet know exist? Are you telling me that electronic microscopes are used in such a way that people actually look into individual massive molecules and... what count the atoms? This is questioning a new technique that's not tested for more than a year for the purpose of being a vaccine. You can tell me that this is in theory safer than traditional vaccines all you want, but by my dumb logic, theory is just that. Traditional vaccine was tested for multiple generations of humans, this was not. I am not advocating traditional vaccine or anything just maybe, maybe, don't feel so sure about things in a field that has so much we don't know yet. mRNA is code created from convoluted processes not exactly like programming code that human specifically write with limited known behaviors.
  - kaba0 5y ago
    So you don’t believe that we can manufacture nucleotide-perfect sequences of RNAs? Than I have to break it for you, we absolutely can, to the point where you can simply order a specific sequence online without much trouble. I just don’t understand why would you trust a car engine all that much more vs medicine. Do not blindly trust anything, but questioning uncontroversially held beliefs by a whole field is just cocky.
    - nsonha 5y ago
      Mechanic is quite simplistic comparing to life science to me. Every single component of the car was built by a spec made by human. We dont borrow components of nature that oporate at a scale we're not fully able to inspect, to produce code we dont fully understand, then claim that the code does exactly what we want and nothing else. Aside from that, cars were also tested for more than 1 year you know?

by nsonha 5y ago

kaba0 5y ago

What do you mean produced? As in the pharmaceutical factory? You can quite literally have a look at it with an electron microscope, and there are trillion other ways to chemically verify that. Also, we can reprogram bacteria to manufacture any protein for us - molecular biology is very advanced. Why do you feel the need to question very basic “problems” that were more than certainly thought about and solved by the many experts working on it for decades? You can question whether the engineers of a car engine though of heat dissipation but you would find it sort of dumb, wouldn’t you?

nsonha 5y ago
> trillion other ways to chemically verify that Trillion? Did you not read what I said about being able to verify the behaviors you want and not the side effects you don't yet know exist? Are you telling me that electronic microscopes are used in such a way that people actually look into individual massive molecules and... what count the atoms? This is questioning a new technique that's not tested for more than a year for the purpose of being a vaccine. You can tell me that this is in theory safer than traditional vaccines all you want, but by my dumb logic, theory is just that. Traditional vaccine was tested for multiple generations of humans, this was not. I am not advocating traditional vaccine or anything just maybe, maybe, don't feel so sure about things in a field that has so much we don't know yet. mRNA is code created from convoluted processes not exactly like programming code that human specifically write with limited known behaviors.
- kaba0 5y ago
  So you don’t believe that we can manufacture nucleotide-perfect sequences of RNAs? Than I have to break it for you, we absolutely can, to the point where you can simply order a specific sequence online without much trouble. I just don’t understand why would you trust a car engine all that much more vs medicine. Do not blindly trust anything, but questioning uncontroversially held beliefs by a whole field is just cocky.
  - nsonha 5y ago
    Mechanic is quite simplistic comparing to life science to me. Every single component of the car was built by a spec made by human. We dont borrow components of nature that oporate at a scale we're not fully able to inspect, to produce code we dont fully understand, then claim that the code does exactly what we want and nothing else. Aside from that, cars were also tested for more than 1 year you know?