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The covid spike protein binds ace2 so the immune response to bind the spike could bind ace2 as well. Normally this is mitigated by a self selection filter but
by sjg007 5y ago
The covid spike protein binds ace2 so the immune response to bind the spike could bind ace2 as well. Normally this is mitigated by a self selection filter but it is not out of the question that you could develop an autoimmune response.
- cma 5y agoThe spike protien binds to ace2 receptors, so the immune response may be more likely to bind to ACE2, which also binds to ace2 receptors, but that isn't a given because the part on the spile the immune response targets don't have to themselves match with parts of ACE2.
- nielsbot 5y agoWould it? My naive guess is that the immune response is an anti-ACE2 match. So it would bind to COVID spike protein, not the ACE2 receptor.