Not eating and not sleeping absolutely wrecks your body. Pair that with a general increase in risky behavior (for example, sexually) and you’ve got a recipe for

Not eating and not sleeping absolutely wrecks your body. Pair that with a general increase in risky behavior (for example, sexually) and you’ve got a recipe for a bad time, eventually. I’m not aware of meth (or its metabolites) being particularly toxic to the cells in the human body (as opposed to cocaine for example, which is directly cardiotoxic if I remember correctly), my understanding is that the bad stuff tends to be the result of behavior that it induces.