4 ms·

Two comments: (1) A friend of mine who works as a doctor in one of the vaccination centers in South Germany told me that re-infection rates with problematic ou

Two comments: (1) A friend of mine who works as a doctor in one of the vaccination centers in South Germany told me that re-infection rates with problematic outcome after full vaccinations are ~5%. This is what they tell their patients in the information talk before the shot. Note that my friend could not give me a higher resolution of the data (age, etc). (2) I think I wrote that in one of my prior comments ~ 9 month or so ago - Another medical doctor aquaintance of mine that was working in the local health department Corona group told me that in the town of Tuttlingen (pop ~ 100K) there habe been 9 re-infections with the SARS-CoV2. At the time there were only 7 known cases in literature.

londons_explore 5y ago
Reinfection rate differing between different studies and populations could partly or entirely be the result of differing error rates in lab processes. Just a 0.1% contamination rate between samples in the lab or hospital would more than explain most of the results.
astrange 5y ago
Is that with AZ or an mRNA vaccine? Also by "problematic", do you know if they meant WHO's "mild" or "severe"? "Mild" is still quite bad, just not enough to hospitalize you.
- wuschel 5y ago
  Hi, sorry for the late reply. Had to get back to my contacts re your questions. I did not check or ask for reference / primary data sources, but I was talking to medical doctor directly involved in the German SARS-CoV2 vaccination program on a local level. > Is that with AZ or an mRNA vaccine? It seems to be unclear by now which combination of vaccination dosages (and their timing) gives the best results. When it comes to double shots, I was told that - AZ: 1 in 5 get infected - Biontech: 1 in 20 get infected > Also by "problematic", do you know if they meant WHO's "mild" or "severe"? "Mild" is still quite bad, just not enough to hospitalize you. Unfortunately, I did not ask regarding these specifics, but I believe that the wording was according to WHO standards. According to my source, after two shots: - AZ: 90% less severe cases, 85% less infections - Biontech: 85% less severe cases, 95% less infections. So, statistically speaking, AZ is better to avoid bad cases, while Biontech is better for spread. In southern Germany, it seems that there is increased activity in administration a combination of both vaccines. This is done because there seems to be an indication that a combination might be better than a mono-vaccine, and/or because of the supply situation / available vaccines. There is a meta study coming out in the UK regarding AZ/Biontech/Moderna vaccine combination and vaccination timing effects. Hope it helps a bit.

londons_explore 5y ago

Reinfection rate differing between different studies and populations could partly or entirely be the result of differing error rates in lab processes. Just a 0.1% contamination rate between samples in the lab or hospital would more than explain most of the results.

astrange 5y ago

Is that with AZ or an mRNA vaccine? Also by "problematic", do you know if they meant WHO's "mild" or "severe"? "Mild" is still quite bad, just not enough to hospitalize you.

wuschel 5y ago
Hi, sorry for the late reply. Had to get back to my contacts re your questions. I did not check or ask for reference / primary data sources, but I was talking to medical doctor directly involved in the German SARS-CoV2 vaccination program on a local level. > Is that with AZ or an mRNA vaccine? It seems to be unclear by now which combination of vaccination dosages (and their timing) gives the best results. When it comes to double shots, I was told that - AZ: 1 in 5 get infected - Biontech: 1 in 20 get infected > Also by "problematic", do you know if they meant WHO's "mild" or "severe"? "Mild" is still quite bad, just not enough to hospitalize you. Unfortunately, I did not ask regarding these specifics, but I believe that the wording was according to WHO standards. According to my source, after two shots: - AZ: 90% less severe cases, 85% less infections - Biontech: 85% less severe cases, 95% less infections. So, statistically speaking, AZ is better to avoid bad cases, while Biontech is better for spread. In southern Germany, it seems that there is increased activity in administration a combination of both vaccines. This is done because there seems to be an indication that a combination might be better than a mono-vaccine, and/or because of the supply situation / available vaccines. There is a meta study coming out in the UK regarding AZ/Biontech/Moderna vaccine combination and vaccination timing effects. Hope it helps a bit.