3 ms·
neutralizing antibodies will give protection against cell entry to the degree they saturate the binding kinetics between receptor and ligand. non neutralizing d
by rolph 5y ago
neutralizing antibodies will give protection against cell entry to the degree they saturate the binding kinetics between receptor and ligand. non neutralizing does not mean ineffective, as ^any^ antibody is a lable that will provoke a complement based immune response, further leading to Tcell based production of antibodies that also include Ab that will bind to domains of spike that are essential to cell entry
- mlyle 5y agoSure, non-neutralizing binding antibodies are also useful. I think you maybe meant to respond to the parent of my comment. The paper shows high binding affinities and high neutralization titers in comparison to convalescent plasma.