3 ms·
The side effects are significant. It comes with some risk of brain bleeds and a high risk of cerebral oedema in patients who have APOe4. This is an important ge
by robbiep 5y ago
The side effects are significant. It comes with some risk of brain bleeds and a high risk of cerebral oedema in patients who have APOe4.
This is an important genetic profile for those who understand Alzheimer’s, as homozygotes for APOe4 are 12x more likely to develop Alzheimer’s.
This is a cop out decision by the FDA. Efficacy can be determined by a RCT - instead a decision was made which supports biogen’s share price