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Question to those who believe the lab leak story: If it came from an animal in the lab where did that animal come from? If it was synthetic, how was it synthe

Question to those who believe the lab leak story: If it came from an animal in the lab where did that animal come from? If it was synthetic, how was it synthesized?

mjfl 5y ago
You are neglecting a third possibility in that it was accidentally generated in lab conditions. The furin cleavage site is a large insert relative to its closest aligning viral genome and is consistent with adaptation to cell culture conditions. The situation would look like someone infecting cells in a dish with some starter virus and continually passaging the supernatant to cells in new dishes, to examine the evolutionary adaptations. This person could have accidentally synthesized SARS-COV-2, and using improper safety protocols, got it on themselves and then went out and infected someone else.
mam3 5y ago
Man you can just look at the lab research papers. They take sars samples from bats and played with them for 10 years, including some paper where they modify the animal-only virus so that it gets into human cells... Its not a conspiracy, its just that accident can happen
dTal 5y ago
Glad you asked! >Shi set out to create novel coronaviruses with the highest possible infectivity for human cells. Her plan was to take genes that coded for spike proteins possessing a variety of measured affinities for human cells, ranging from high to low. She would insert these spike genes one by one into the backbone of a number of viral genomes (“reverse genetics” and “infectious clone technology”), creating a series of chimeric viruses. These chimeric viruses would then be tested for their ability to attack human cell cultures (“in vitro”) and humanized mice (“in vivo”)... It cannot yet be stated that Shi did or did not generate SARS2 in her lab because her records have been sealed, but it seems she was certainly on the right track to have done so. https://thebulletin.org/2021/05/the-origin-of-covid-did-people-or-nature-open-pandoras-box-at-wuhan/ https://thebulletin.org/2021/05/the-origin-of-covid-did-peop...
choward 5y ago
It's not about "believing in the lab leak theory" or "believing in the science". It's about being able to question things without being cancelled or censored. Journalism and science are both supposed to be about questioning things and getting to the bottom of them. When you can't do that you have a huge problem. For the last year people have been censored on social media for even suggesting that a lab leak was possible.

Question to those who believe the lab leak story: If it came from an animal in the lab where did that animal come from? If it was synthetic, how was it synthesized?

mjfl 5y ago

You are neglecting a third possibility in that it was accidentally generated in lab conditions. The furin cleavage site is a large insert relative to its closest aligning viral genome and is consistent with adaptation to cell culture conditions. The situation would look like someone infecting cells in a dish with some starter virus and continually passaging the supernatant to cells in new dishes, to examine the evolutionary adaptations. This person could have accidentally synthesized SARS-COV-2, and using improper safety protocols, got it on themselves and then went out and infected someone else.

mam3 5y ago

Man you can just look at the lab research papers. They take sars samples from bats and played with them for 10 years, including some paper where they modify the animal-only virus so that it gets into human cells... Its not a conspiracy, its just that accident can happen

dTal 5y ago

Glad you asked! >Shi set out to create novel coronaviruses with the highest possible infectivity for human cells. Her plan was to take genes that coded for spike proteins possessing a variety of measured affinities for human cells, ranging from high to low. She would insert these spike genes one by one into the backbone of a number of viral genomes (“reverse genetics” and “infectious clone technology”), creating a series of chimeric viruses. These chimeric viruses would then be tested for their ability to attack human cell cultures (“in vitro”) and humanized mice (“in vivo”)... It cannot yet be stated that Shi did or did not generate SARS2 in her lab because her records have been sealed, but it seems she was certainly on the right track to have done so. https://thebulletin.org/2021/05/the-origin-of-covid-did-people-or-nature-open-pandoras-box-at-wuhan/ https://thebulletin.org/2021/05/the-origin-of-covid-did-peop...

choward 5y ago

It's not about "believing in the lab leak theory" or "believing in the science". It's about being able to question things without being cancelled or censored. Journalism and science are both supposed to be about questioning things and getting to the bottom of them. When you can't do that you have a huge problem. For the last year people have been censored on social media for even suggesting that a lab leak was possible.