4 ms·

It probably goes without saying, but don’t try this at home with ketamine you score off the grey or dark web. I am generally a fan of the occasional self-presc

It probably goes without saying, but don’t try this at home with ketamine you score off the grey or dark web. I am generally a fan of the occasional self-prescribed party drug, but if you suffer from severe depressive disorder, you should not do this without proper supervision. (And no, doing a bump off someone’s mailbox key is not proper supervision. Fun! Not medically wise, though.)

tayo42 5y ago
Why? If you test it and have the same dosage it seems to be the same thing? isn't ketamine treatment just taking it and letting the chemical work. Why would your supplier being any different matter?
- after_care 5y ago
  Self medicating drugs with high abuse potential is very risky. Having tightly controlled doses, intervals between doses, settings for administering the doses can offset much of the abuse and addiction potential.
  - smabie 5y ago
    While I have known a couple of people who've gotten addicted to ketamine to their detriment, the vast majority of users have no such problems. Like everything else in life, upsides have to be weighed with the downsides. For people who can't afford clinical ketamine treatment and are depressed, I don't see anything wrong with just buying some ketamine on the black market.
    - splithalf 5y ago
      The same can and often has been said of cocaine. Not that the two are the same, but everything you said is the same, vast majority have no problems, it’s great, you’ll love it etc....
      - smabie 5y ago
        I mean, honestly haven't met that many people who've had a problem with cocaine either. Opiates on the other hand, that's a different story.
  - cies 5y ago
    Do you have a source on this? I dont believe we'd have any more addicts when we'd go with total legalization. Portugal is a great example (albeit they did not legalize but decriminalize). This fear mongering on "freedom to use what every you like" should stop. It serves no purpose but keeping prisons full and street drug in bad quality. Why would we want to pay so much tax for that? Every politician who claims to be in favor of "freedom", but cannot deal with the freedom to use what ever you like is a fraud.
  - TulliusCicero 5y ago
    > Self medicating drugs with high abuse potential is very risky. Granted, but is it more or less risky for a person to remain severely depressed, if regular medications don't work?
    - aidenn0 5y ago
      People recovering from a major depressive episode are at a very high risk of suicide. People who are currently depressed are usually insufficiently motivated to kill themselves. If we think ketamine therapy will soon be covered by insurance it may be lower risk to wait.
      - TulliusCicero 5y ago
        Okay, but one of those is a transition phase and the other is steady state. Anyway, do you have a source for that?
- WarOnPrivacy 5y ago
  > isn't ketamine treatment just taking it and letting the chemical work. Generally, no. Self-administering a psychotherapeutic drug, while isolated and without training, can have the lowest likelyhood of a positive outcome. Having an experienced guide or trained therapist present - someone to provide appropriate nudges/direction/counseling or sometimes just for company - this is where we often see experiences with huge, lasting benefits.
  - tayo42 5y ago
    why are you saying "we"? The point of the ketamine treatment is because of an interaction in your brain's receptors, at least that's the theory. If its just chemical why is counseling necessary?
    - WarOnPrivacy 5y ago
      > why are you saying "we"? Shorthand. You can substitute 'is', if that helps. > If its just chemical why is counseling necessary? It isn't just chemical.
      - tayo42 5y ago
        We makes it sounds like your actively involved in giving this therapy and then in this case speaking from a position of authority. Nothing Ive read suggests there is some talk therapy or integration side to this. Like some guides say close your eyes and listen to music. Almost everything I've read talks about its interaction with glutamate other chemicals.
- perardi 5y ago
  Have you…done ketamine? Ketamine can be intense. I would not like to take a clinical dose of K, while in a depressed state, sans supervision.
  - tayo42 5y ago
    i actually have... https://pubmed.ncbi.nlm.nih.gov/28749092/ https://pubmed.ncbi.nlm.nih.gov/28749092/ > Ketamine is most commonly administered in the dose of 0.5 mg/kg, but some patients may respond to doses as low as 0.1 mg/kg, and others may require up to 0.75 mg/kg. This is about 40mg for someone my size. Its not a khole

tayo42 5y ago

Why? If you test it and have the same dosage it seems to be the same thing? isn't ketamine treatment just taking it and letting the chemical work. Why would your supplier being any different matter?

after_care 5y ago
Self medicating drugs with high abuse potential is very risky. Having tightly controlled doses, intervals between doses, settings for administering the doses can offset much of the abuse and addiction potential.
- smabie 5y ago
  While I have known a couple of people who've gotten addicted to ketamine to their detriment, the vast majority of users have no such problems. Like everything else in life, upsides have to be weighed with the downsides. For people who can't afford clinical ketamine treatment and are depressed, I don't see anything wrong with just buying some ketamine on the black market.
  - splithalf 5y ago
    The same can and often has been said of cocaine. Not that the two are the same, but everything you said is the same, vast majority have no problems, it’s great, you’ll love it etc....
    - smabie 5y ago
      I mean, honestly haven't met that many people who've had a problem with cocaine either. Opiates on the other hand, that's a different story.
- cies 5y ago
  Do you have a source on this? I dont believe we'd have any more addicts when we'd go with total legalization. Portugal is a great example (albeit they did not legalize but decriminalize). This fear mongering on "freedom to use what every you like" should stop. It serves no purpose but keeping prisons full and street drug in bad quality. Why would we want to pay so much tax for that? Every politician who claims to be in favor of "freedom", but cannot deal with the freedom to use what ever you like is a fraud.
- TulliusCicero 5y ago
  > Self medicating drugs with high abuse potential is very risky. Granted, but is it more or less risky for a person to remain severely depressed, if regular medications don't work?
  - aidenn0 5y ago
    People recovering from a major depressive episode are at a very high risk of suicide. People who are currently depressed are usually insufficiently motivated to kill themselves. If we think ketamine therapy will soon be covered by insurance it may be lower risk to wait.
    - TulliusCicero 5y ago
      Okay, but one of those is a transition phase and the other is steady state. Anyway, do you have a source for that?
WarOnPrivacy 5y ago
> isn't ketamine treatment just taking it and letting the chemical work. Generally, no. Self-administering a psychotherapeutic drug, while isolated and without training, can have the lowest likelyhood of a positive outcome. Having an experienced guide or trained therapist present - someone to provide appropriate nudges/direction/counseling or sometimes just for company - this is where we often see experiences with huge, lasting benefits.
- tayo42 5y ago
  why are you saying "we"? The point of the ketamine treatment is because of an interaction in your brain's receptors, at least that's the theory. If its just chemical why is counseling necessary?
  - WarOnPrivacy 5y ago
    > why are you saying "we"? Shorthand. You can substitute 'is', if that helps. > If its just chemical why is counseling necessary? It isn't just chemical.
    - tayo42 5y ago
      We makes it sounds like your actively involved in giving this therapy and then in this case speaking from a position of authority. Nothing Ive read suggests there is some talk therapy or integration side to this. Like some guides say close your eyes and listen to music. Almost everything I've read talks about its interaction with glutamate other chemicals.
perardi 5y ago
Have you…done ketamine? Ketamine can be intense. I would not like to take a clinical dose of K, while in a depressed state, sans supervision.
- tayo42 5y ago
  i actually have... https://pubmed.ncbi.nlm.nih.gov/28749092/ https://pubmed.ncbi.nlm.nih.gov/28749092/ > Ketamine is most commonly administered in the dose of 0.5 mg/kg, but some patients may respond to doses as low as 0.1 mg/kg, and others may require up to 0.75 mg/kg. This is about 40mg for someone my size. Its not a khole