2 ms·
We still don't have enough data on whether this will suffer ADE. If parent is young, isn't in a highly infectious area and behaves cautiously, they may be makin
by swader999 5y ago
We still don't have enough data on whether this will suffer ADE. If parent is young, isn't in a highly infectious area and behaves cautiously, they may be making a less risky decision.
- amluto 5y agoWe absolutely have enough data to rule out meaningful ADE. Study after study (the phase 3 trials and all the ongoing surveillance) indicates a massive reduction in the rate of severe infection among vaccine recipients. Sure, one can quibble about whether maybe some of the very small number of people who got a vaccine more than a couple weeks before a severe COVID case had a form of ADE, but that’s like saying that we haven’t ruled out that seatbelts might kill people. In both cases, the risk that a protective measure harms the recipient is massively outweighed by the degree to which the protective measure protects the recipient.
- swader999 5y agoADE doesn't really show up until years later with different strains and different virus.
- amluto 5y agoBy that standard, you also can’t rule out disease-induced ADE, dengue style. But the vaccine developers do know what they’re doing. IIRC, with SARS, a lot of research was done that suggested that antibodies against N might cause ADE but antibodies against S would not. If that carries over to COVID, then maybe one is better off with a vaccine than natural disease: the latter induces antibodies against N but the former does not.
- tylerhou 5y agoCovid infection produced antibodies can also cause ADE, so that's not a great argument against immunization.