4 ms·

Is having? Where? I see nothing that leads to me believe the evidence-free hype around longevity. I think it's early to say it's happening now. Eventually? Sure

Is having? Where? I see nothing that leads to me believe the evidence-free hype around longevity. I think it's early to say it's happening now. Eventually? Sure...maybe.

chpatrick 5y ago
Being able to produce any protein in the body with mRNA seems like a pretty big leap.
- hulitu 5y ago
  Bio(n)tech is Godzilla.
  - inglor_cz 5y ago
    Oh, a Sepultura fan. They were big in the Czech Republic in the early 1990s. A Brazilian band, but resonated with Central European metalheads a lot.
- Someone 5y ago
  So do understanding the role of DNA and understanding it’s chemistry: necessary, but not sufficient. I think mRNA production will help in quite a few rare genetic diseases, but also that we’re far away from being able to safely make the myriads of subtle changes needed to make otherwise healthy people live longer. I compare it to heart surgery. It is quite a miracle that we can do it, but the risks are so high that we only do it when people’s hearts have lost significant portion of their pumping capacity. You don’t see cross-country skiers who are just not good enough get heart surgery to make it to the olympics, for example.
  - deleted 5y ago
    [deleted]
nscalf 5y ago
We can now make the safest, most effective vaccines ever in 2 days. We're making huge advancements with mRNA. CRSPR is still a new technology that is being rapidly improved. Last years big biotech story was that we have more or less solved the protein folding problem, which effectively gives us strong predictive power. So yes, it's happening now. We're still in the early stages of it, but it is without a doubt happening. Edit: adding from a comment below, there are real world instances of lab grown tissues being transplanted into patients. That is also in the early stages, but has evidence of real world progress.
- TaupeRanger 5y ago
  mRNA gave us a vaccine - very good but not a revolution by any means. We would've gotten effective vaccines from other sources. Nothing else has done anything. CRISPR hasn't done anything in humans. Protein folding prediction hasn't done anything. Lab grown tissue hasn't done anything in humans. It is not happening in any way.

Is having? Where? I see nothing that leads to me believe the evidence-free hype around longevity. I think it's early to say it's happening now. Eventually? Sure...maybe.

chpatrick 5y ago

Being able to produce any protein in the body with mRNA seems like a pretty big leap.

hulitu 5y ago
Bio(n)tech is Godzilla.
- inglor_cz 5y ago
  Oh, a Sepultura fan. They were big in the Czech Republic in the early 1990s. A Brazilian band, but resonated with Central European metalheads a lot.
Someone 5y ago
So do understanding the role of DNA and understanding it’s chemistry: necessary, but not sufficient. I think mRNA production will help in quite a few rare genetic diseases, but also that we’re far away from being able to safely make the myriads of subtle changes needed to make otherwise healthy people live longer. I compare it to heart surgery. It is quite a miracle that we can do it, but the risks are so high that we only do it when people’s hearts have lost significant portion of their pumping capacity. You don’t see cross-country skiers who are just not good enough get heart surgery to make it to the olympics, for example.
- deleted 5y ago
  [deleted]

nscalf 5y ago

We can now make the safest, most effective vaccines ever in 2 days. We're making huge advancements with mRNA. CRSPR is still a new technology that is being rapidly improved. Last years big biotech story was that we have more or less solved the protein folding problem, which effectively gives us strong predictive power. So yes, it's happening now. We're still in the early stages of it, but it is without a doubt happening. Edit: adding from a comment below, there are real world instances of lab grown tissues being transplanted into patients. That is also in the early stages, but has evidence of real world progress.

TaupeRanger 5y ago
mRNA gave us a vaccine - very good but not a revolution by any means. We would've gotten effective vaccines from other sources. Nothing else has done anything. CRISPR hasn't done anything in humans. Protein folding prediction hasn't done anything. Lab grown tissue hasn't done anything in humans. It is not happening in any way.