>I was under the impression that any mutations to the spike proteins would make the current vaccines useless and would require changes to the vaccines just like

>I was under the impression that any mutations to the spike proteins would make the current vaccines useless and would require changes to the vaccines just like the flu shot . Isn't this the case ? No, it is not the case. You don't just make one antibody that targets the entire spike that would be thrown off by a mutation. >Human Antibodies Target Many Parts of Coronavirus Spike Protein https://directorsblog.nih.gov/2021/05/18/human-antibodies-target-many-parts-of-coronavirus-spike-protein/ https://directorsblog.nih.gov/2021/05/18/human-antibodies-ta... So far, all the claims that a variant (London variant, South African variant, Indian variant) would be immune to the current vaccine have turned out to be unwarranted.