6 ms·

tl;dr - too much modafinil. Yes, I have Crohn's and I do not like to take the meds or listen to the doctors. This is NOT AT ALL SOMETHING I RECOMMEND, PLEASE D

tl;dr - too much modafinil. Yes, I have Crohn's and I do not like to take the meds or listen to the doctors. This is NOT AT ALL SOMETHING I RECOMMEND, PLEASE DO NOT ATTEMPT IT. Crohn's is an auto-immune disease and the main class of drugs that is used to treat Crohn's like mine (long term) are called TNF inhibitors or TNF blockers. TNF alpha triggers the production of several immune system molecules, including interleukin-1 and interleukin-6. I realized I can track this with basic inflammatory marker test, I also realized that I could use diet to impact my markers. So instead of taking what is referred to as a Biologic e.g.: Adalimumab, Certolizumab etc... I started using NIO to try and get the same effect. I got a pill making machine, and learned how to make supplements but they were not working well enough so I knew I needed something stronger. Then I found this article: https://pubmed.ncbi.nlm.nih.gov/32311496/ https://pubmed.ncbi.nlm.nih.gov/32311496/ I think it was on HN but I do not remember for sure. I order some modafinil and worked it into my mixture. I do not manually create my mixtures because I do not want to know which version I am on, I want my symptoms to go away and that should be the trigger to tell me if its working. So I have a 14 vile setup with an audrino all wired into my press and based on my food diary (e.g.: nutrient intake) it decides how much of what should go into a run. e.g.: how much burdok, tumeric, serrapeptase etc... I got something wrong and ended up adding far too much to a run of pills, I didn't realize this until i started ti see floaters in my eye and I checked to see how much moda was left and it was far less than should have been left. Then i did some reading and a side effect of taking too much moda can be detached retnas, since I have all the symptoms: Floaters, stars and peripheral flashes I am assuming that based on the timing I now have detached retnas, I also found my mistake and essentially no matter where my markers were I was getting about 600mg of moda per day. Which is far more than should be taken. This was for about a 1 month period. I have fixed the issue now and I have a much more sophisticated pipeline but I will have to get this fixed. NOTE: I am not a doctor, I have no college education or anything like that. I just like bio-hacking and decided to pursue my moonshot during the pandemic. I can explain more or provide pics and vids to explain further if you like, email in profile. I am currently writing up a 100% independent non peer reviewed case study to document everything I have done and the results.

ed25519FUUU 5y ago
Wow. I both respect you and think you’re absolutely nuts. Since you seem to be into experimental treatment, have you ever tried helminthic treatment? https://www.healthline.com/health/crohns-disease/hook-worms https://www.healthline.com/health/crohns-disease/hook-worms
- kortex 5y ago
  Not OP, but I have done this for allergies. N. Americanus, 10-15 eggs at a time. No side effects other than an awful itch 12-36h after administration. Been great for my allergies. I've cut way down on fexofenadine. I also live with a cat and a poodle and only really feel symptoms if I literally rub my face in the cat, or groom the dog inside without a mask.
  - arionhardison 5y ago
    If you would ever be willing to discuss your work and hear about mine, that would be awesome. AGAIN, I AM NOT A DOCTOR. But I really love this stuff and have started to study for MCAT just so I know more and dont feel like such a moron.
  - theli0nheart 5y ago
    That sounds horrible. Why?
- arionhardison 5y ago
  Yes, it is one of the therapies I am currently studying as I have had success with it but it does not scale. The reason I want to do this is so that I can create a Medicare/Medicaid E2E single payer solution that provides these solutions to everyone. Even people on the lower socioeconomic rungs. The pandemic was really hard for me and I have been behaving very recklessly in terms of my own health but I have been very responsible in terms of other people health. I was running an outpatient program for alternative therapies before I knew that you cant just do that, you need insurance and stuff. So now I am making my own Medicare/Medicaid and hope to bring all of my work into a single payer system. There is no way I can pull this off, my only hope is to attract the attention of some really smart people that will tell me why and how I am a moron and how to fix it, lol. I would love to talk about my work with someone but i'm kind of still scared because its not in a state that is 100% ready for end users and I know everyone is just going to laugh at me, lol. Hell I laugh at me. But I worked at goop and i know more than everyone there so i'm kind of like ... fuck it. Just code / Fierce Nerd blah blah <insert-some-rationalization-here>. Right now I am having fun exploring the world of BHM HMS modules, its far less regulated than I thought it would be which might not be a good thing, but we will see. I am going to do a "Show HN" soon but I want to publish feedback from my active patients and providers first.

ed25519FUUU 5y ago

Wow. I both respect you and think you’re absolutely nuts. Since you seem to be into experimental treatment, have you ever tried helminthic treatment? https://www.healthline.com/health/crohns-disease/hook-worms https://www.healthline.com/health/crohns-disease/hook-worms

kortex 5y ago
Not OP, but I have done this for allergies. N. Americanus, 10-15 eggs at a time. No side effects other than an awful itch 12-36h after administration. Been great for my allergies. I've cut way down on fexofenadine. I also live with a cat and a poodle and only really feel symptoms if I literally rub my face in the cat, or groom the dog inside without a mask.
- arionhardison 5y ago
  If you would ever be willing to discuss your work and hear about mine, that would be awesome. AGAIN, I AM NOT A DOCTOR. But I really love this stuff and have started to study for MCAT just so I know more and dont feel like such a moron.
- theli0nheart 5y ago
  That sounds horrible. Why?
arionhardison 5y ago
Yes, it is one of the therapies I am currently studying as I have had success with it but it does not scale. The reason I want to do this is so that I can create a Medicare/Medicaid E2E single payer solution that provides these solutions to everyone. Even people on the lower socioeconomic rungs. The pandemic was really hard for me and I have been behaving very recklessly in terms of my own health but I have been very responsible in terms of other people health. I was running an outpatient program for alternative therapies before I knew that you cant just do that, you need insurance and stuff. So now I am making my own Medicare/Medicaid and hope to bring all of my work into a single payer system. There is no way I can pull this off, my only hope is to attract the attention of some really smart people that will tell me why and how I am a moron and how to fix it, lol. I would love to talk about my work with someone but i'm kind of still scared because its not in a state that is 100% ready for end users and I know everyone is just going to laugh at me, lol. Hell I laugh at me. But I worked at goop and i know more than everyone there so i'm kind of like ... fuck it. Just code / Fierce Nerd blah blah <insert-some-rationalization-here>. Right now I am having fun exploring the world of BHM HMS modules, its far less regulated than I thought it would be which might not be a good thing, but we will see. I am going to do a "Show HN" soon but I want to publish feedback from my active patients and providers first.