I'm wondering if the Moderna vaccine acts similarly, and innate training occurs mostly during the first shot seeing the VLPs and/or spike proteins. Then, perhap

I'm wondering if the Moderna vaccine acts similarly, and innate training occurs mostly during the first shot seeing the VLPs and/or spike proteins. Then, perhaps more of the adaptive system generating IgGs is trained weeks after the first shot and/or reinforced during the second shot which triggers a large response, hence flu-like symptoms. Additional shots or pathogen exposure would likely not produce much of a response as it seems the innate system participates, in addition to the adaptive system. It might be because humoral and cellular elements straddle both systems, and perhaps they cooperate in some form even if they're operating in mostly different domains. On the fungi cytokine increased responses front, I wonder if the alterations in toll-like receptors heightens fungal allergies in addition to fighting fungal infections more efficiently.