Just to make things a bit more interesting (and grim): every HIV patient has multiple variants at the same time. In this regard HIV is pretty much like cancer :

Just to make things a bit more interesting (and grim): every HIV patient has multiple variants at the same time. In this regard HIV is pretty much like cancer :( > Nucleotide sequences of the hypervariable V3 region of HIV-1 obtained from different organs of one patient demonstrated distinct viral variants. https://pubmed.ncbi.nlm.nih.gov/8151287/ https://pubmed.ncbi.nlm.nih.gov/8151287/