Yeah, you're basically scrambling things across an entire genome with no way to account for all of the random and unspecific changes that may occur. One thing

Yeah, you're basically scrambling things across an entire genome with no way to account for all of the random and unspecific changes that may occur. One thing to consider though is that our bodies have evolved to eat all sorts of DNA - fragments and full genes - without directly incorporating it into our own genomes. I'd personally be more concerned about plants expressing new allergenic proteins or that sort of thing, but it seems like there are already some decent methods in use to detect that.