3 ms·
My partner is the recipient of an organ transplant and is on anti-rejection meds. She's already had both shots of Pfizer. So we're following the research closel
by dunnevens 5y ago
My partner is the recipient of an organ transplant and is on anti-rejection meds. She's already had both shots of Pfizer. So we're following the research closely. Researchers are beginning to look at how the vaccine works in the immunosuppressed. The initial results aren't great. In one study[1], 46% didn't have any antibodies after both shots. 39% had antibodies only after the second shot. Only 15% received antibodies after the first shot.
I know this research is still in early stages and the initial sample size was relatively small. And T-cell responses were not measured. There's a decent chance the situation isn't as bad as it initially seems. But it's still discouraging.
[1] Antibody Response to 2-Dose SARS-CoV-2 mRNA Vaccine Series in Solid Organ Transplant Recipients
https://jamanetwork.com/journals/jama/fullarticle/2779852 https://jamanetwork.com/journals/jama/fullarticle/2779852
- meepmorp 5y agoI'm assuming the J&J/other viral vaccines are a no-go with the immunosupressants. Hopefully, additional mRNA boosters can improve the immune response.