3 ms·
Half of my comments start with "I heard a podcast the other day about this.." but I heard a podcast the other day that described how they had managed to get pig
by gadders 5y ago
Half of my comments start with "I heard a podcast the other day about this.." but I heard a podcast the other day that described how they had managed to get pigs to survive for multiple hours by inserting oxygenated liquid into their anus.
"Takanori - One is a very intuitive approach we just intubated, from the anus, just to provide oxygen gas continuously. This oxygen delivery is really able to persist survival in lethal conditions. Even up to 60 minutes or even longer.
Eva - 60 minutes of breathing through the rectum just by pumping in oxygen. Sounds amazing, but also like you could get a bit uncomfortable. The more clinically relevant approach uses a liquid that's very good at dissolving oxygen, perfluorocarbon or PFC. This liquid is already used by doctors during some ice surgeries and sometimes as a type of synthetic blood for transfusions. So we already know that it's safe for humans.
Takanori - So that liquid ventilation approach is also having greater impacts on oxygenation. So as to really rescue those fatal hypoxic conditions in the mouse, rats, and pig model system.
Eva - Incredibly, Takanori showed that when just less than a pint of this PFC was injected into the anus of pigs, they would stay happily oxygenated for up to 20 minutes when in respiratory failure. And they didn't stop there, by re-injecting every 20 minutes or so they could keep the pigs going for hours, or even more. Importantly though, when we breathe in and out using our lungs, we aren't just taking in oxygen. We're getting rid of carbon dioxide and other waste products too."
Transcript of interview: https://www.thenakedscientists.com/articles/interviews/intestinal-breathing-success-during-hypoxia https://www.thenakedscientists.com/articles/interviews/intes...
NY Times article: https://www.nytimes.com/2021/05/14/science/rectum-breathing-oxygen.html https://www.nytimes.com/2021/05/14/science/rectum-breathing-...
//EDIT//Actual paper: https://www.cell.com/med/fulltext/S2666-6340(21)00153-7?utm_source=EA https://www.cell.com/med/fulltext/S2666-6340(21)00153-7?utm_...